Role Title: Senior Scientist (UK Soluble Biomarkers – Immunoassay)
Duration: 12 Months
Location: Stevenage
Rate: £23.20 per hour PAYE
Who Are We - GSK?
We are a science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. GlaxoSmithKline plc was formed in 2000 as a result of a merger between Glaxo Wellcome plc and SmithKline Beecham plc, although our history can be traced back more than 300 years to London's Plough Court Pharmacy in the 1700s.
Our goal is to be one of the world's most innovative, best performing and trusted healthcare companies. Our strategy is to bring differentiated, high-quality and needed healthcare products to as many people as possible, with our three global businesses, scientific and technical know-how and talented people. Our values and expectations are at the heart of everything we do and form an important part of our culture:
- Our values are Patient focus, Transparency, Respect, Integrity
- Our expectations are Courage, Accountability, Development, Teamwork
Role purpose / summary
We are seeking a motivated Bioanalytical scientist to join our group based at our flagship R&D site in Stevenage, Hertfordshire. The team supports soluble biomarker measurements for clinical studies using a variety of ligand binding assay techniques. The data we generate is critical to helping GSK Project Teams make decisions on progressing new molecules towards becoming medicines.
In this role you will assist in the validation of bespoke immunoassays for soluble biomarker endpoints in support of early stage clinical trials. You will be responsible for the delivery of high-quality large molecule bioanalytical assay data to study teams for early stage clinical studies (e.g. enabling and FTiH). We are looking for a team member who is keen to further their career in immunoassay analysis alongside complimentary automation techniques.
Responsibilities:
- Conduct analysis of human biological samples using immunoassays whilst being fully compliant with GCP regulatory requirements
- Holding yourself accountable for delivering high quality bioanalytical results & managing timelines
- Build effective relationships with the various supported groups within and outside the department
- Work as part of the team to ensure day-to-day laboratory responsibilities are met (reviewing study plans/reports, QC checking colleagues work, safety inspections, instrument maintenance etc)
- Partner with external companies and institutes to deliver laboratory solutions
- Drive innovation and actively contribute to process improvements (scientific, regulatory/quality)
Key Skills/ requirements
Essential Criteria (Why You?):
- Graduate degree in biology, biochemistry or pharmacology
- Experience running Bioanalytical or Biomarker assays, preferably in a GxP regulated environment, with a focus on good record keeping and data integrity
- Ability to effectively manage multiple priorities, communicate recommendations clearly and enjoy working within a team
- Ability to present both written and oral communications to R&D stakeholders
The following criteria would also be desirable:
- Understanding of regulatory aspects of human biological sample management, Good Clinical Practice (GCP)
- Experience in the method development and validation of immunoassays using one or more of the following; Gyrolab, MSD, Simoa, SMCxPRO or ELISpot
- Experience of interacting with LabQA/regulatory inspectors
- Experience in tailoring bespoke biomarker assay validations to the context of use for the data
- Experience with automated liquid handling platforms (e.g. Labcyte Echo, SPT Labtech DragonFly, Agilent BRAVO, Hamilton STAR)
- Experience using Thermo Watson LIMS
Please Note: This role is an on-site position and the successful applicant will be based at GSK's Stevenage R&D site. A key responsibility of the position involves working with human biological samples and so Hepatitis B vaccination is required, along with evidence of titre, prior to the commencement of work.
Please consider the commute/travel when applying for the role.
All profiles will be reviewed against the required skills and experience. Due to the high number of applications we will only be able to respond to successful applicants in the first instance. We thank you for your interest and the time taken to apply!
Join GSK's vision to do more, feel better and live longer:
https://user/gskvision/
Who will I be working with?
http://en-gb/careers/meet-our-people/