About the Role
This post will provide technical support for the Flow Cytometry Service at the Barts Cancer Institute(BCI)/WHRI. The post-holder will be responsible for day-to-day operation, maintenance and quality control of cell-sorters/analysers and provide users support at all levels. A collaborative approach is essential to cover duties during colleagues' absences or high-demand periods. Prior knowledge and hands-on experience with BDFACSAria sorters and analysers, along with a strong understanding of Diva software and multicolour Flow Cytometry principles, are essential. Additional training can be provided if needed.
About You
You should have a relevant BSc or equivalent, with a strong background in cancer cell biology or immunology, along with the ability to design, conduct, and analyse complex flow cytometry-based cell assays. Knowledge of PBMC preparation, cell, and tissue culture is desirable. The ideal candidate will be detail oriented, motivated to learn, capable of working both independently and as part of a team, with strong organizational skills, effective communication, and a focus on customer service. Prior experience in a flow cytometry core lab is highly desirable.
About the Institute
BCI is a Cancer Research UK Centre of Excellence whose work aims to transform the lives of those with/at risk of cancer through laboratory-based innovative research, in patients and populations. BCI is internationally renowned in many areas of cancer research. It combines ground-breaking basic research with the expertise of clinicians and scientists from the Centre for Experimental Cancer Medicine and the Barts NHS Trust to achieve improvements in cancer patient care. BCI is also a partner in the CRUK City of London Major Centre, which is a Centre of Excellence in Biotherapeutics. It's one of six institutes within The School of Medicine and Dentistry.
Further information on the responsibilities will be provided upon shortlisting.
Experience / Skills
EXPERIENCE
Experience in the operation of flow cytometers
Experience in cell sorting
Experience in other biochemical techniques
Experience with statistical analysis (Desirable)
Experience of working in a biomedical research laboratory
Experience with computer software relevant to laboratory research, data presentation and statistical evaluation of results
Knowledge of the principles of flow cytometry
Experience of working in a core service laboratory (Desirable)
Experience in multiparameter (>10) cell sorting and cytometric analysis, on a variety of cytometers
Experience with Liquid and Imaging mass cytometry (Desirable)
Experience with Imaging Flow cytometry (Desirable)
Experience with Spectral Flow cytometry (Desirable)
Knowledge of flow cytometry analysis software
SKILLS
Ability to follow written and oral instructions
Ability to maintain accurate and up to date records
Understanding of the research process
Ability to organise and prioritise own work and organise research within the project timetable
Computer literacy
Evidence of good team-working
Good communication skills
Analytical skills
Experience with data analysis and presentation
Flexible and co-operative
Self-motivated and hardworking
Willingness to work flexibly in order to achieve project demands
Willingness to learn new skills
The ability to meet UK right to work requirements.